190 / 1835
298
293
298
286
HD10: Long-term outcome
10 year estimate [95%-CI] Hazard Ratio [95%-CI]
4ABVD+30Gy
87.4% [82.9% to 91.9%]
2ABVD+20Gy
87.2% [82.9% to 91.5%]
1.0 [0.6 to 1.5]
Difference
-0.2% [-6.4% to 6.0%]
Median observation time 98 months
10 year estimate [95%-CI] Hazard Ratio [95%-CI]
4ABVD+30Gy
93.6% [90.5% to 96.7%]
2ABVD+20Gy
94.1% [91.1% to 97.1%]
0.9 [0.5 to 1.6]
Difference
0.5% [-3.8% to 4.9%]
Median observation time 113 months
No difference in 10-year PFS and OS between most and least
intensive arms of therapy (i.e. 4 vs. 2xABVD and 20 vs. 30Gy IF-RT)