198 / 1835
No difference in 15-year PFS and OS between consolidative EF and IF-RT
after 2x COPP/ABVD in early-stage unfavorable HL.
532
517
15 year estimate [95%-CI]
EF: 72.7% [68.2% to 77.2%]
IF:
73.8% [69.2% to 78.3%]
diff: 1.1% [-5.3% to 7.5%]
Hazard Ratio 0.98 [0.76 to 1.25]
Median observation time 153 months
532
523
15 year estimate [95%-CI]
EF: 80.5% [76.7% to 84.3%]
IF:
82.4% [78.7% to 86.0%]
diff: 1.8% [-3.4% to 7.1%]
Hazard Ratio 0.88 [0.66 to 1.16]
Median observation time 174 months
PFS
OS
Bröckelmann et al; EHA 2016
HD8: Long-term Outcome