564 / 1835
Toxicity
Adverse Event in
At least 10%
Worst Grade
Grade 3-4
N(%)
Neutropenia
104 (95.4)
Thrombocytopenia
101 (92.7)
Infection
69 (63.3)
Mucositis
38 (34.9)
Anaemia
32 (29.4)
Fever
19 (17.4)
Febrile
Neutropenia
18 (16.5)
Pain
17 (15.6)
Leukopenia
13 (11.9)
Diarrhoea
12 (11.0)
Nausea
12 (11.0)
Anorexia
11 (10.1)
Any grade 3/4 AE
108 (99.1)
•All patients experienced at least
one grade 3+ adverse event
(AE)
•Five treatment related deaths
were recorded:
•all 5 were PS 3
•ages: 53,55, 56, 56 and 60