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intermittent irradiation: loss of effect?

SCCVII (vitro)

(5 X 1.6 Gy)

SCCVII (vivo)

(5 X 4 Gy)

(Tomita et al, 2008)

in vitro: loss of effect with short intervals

in vivo: recovery of sublethal damage compensated by reoxygenation