136 / 1173
Intrinsic Pathway – Mitochondria dependent
• Mitochondria induce apoptosis when pro-apoptotic
factors outnumber anti-apoptotic factors
Step 1)
Increase in the balance of
proapoptotic to antiapoptotic
factors (Bax/Bcl2)
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|
136 / 1173
Intrinsic Pathway – Mitochondria dependent
• Mitochondria induce apoptosis when pro-apoptotic
factors outnumber anti-apoptotic factors
Step 1)
Increase in the balance of
proapoptotic to antiapoptotic
factors (Bax/Bcl2)