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ESTRO

Meta-analysis on altered fractionation HNSCC

Bourhis, Pignon 2006

Randomized trials 1970-1998 (no postop RT)

15 trials included (6515 patients, individual data)

p <0.0001

100

80

60

40

20

0

100

80

60

40

20

0

Loco-regional recurrence

Overall survival