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!

RBE is the ratio of the dose of some “standard”

radiation to the dose of the radiation of interest

to produce the same biological effect

!

The “standard” radiation is either orthovoltage

X rays (~250 kVp) or

60

Co gamma rays

!

RBE increases with increase in LET up to a

maximum at ~100 keVµm

-1

, and thereafter

decreases due to the “overkill” effect

Conclusions 3