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Name
Target
Company
Class
Bevacizumab
VEGF
Genentech
Monoclonal antibody
BIBW 2992 (Tovok)
EGFR and Erb2
Boehringer Ingelheim
Small molecule
Cetuximab
EGFR
Imclone/BMS
Monoclonal antibody
Imatinib
Bcr-Abl
Novartis
Small molecule
Trastuzumab
Erb2 (Her2)
Genentech/Roche
Monoclonal antibody
Gefitinib
EGFR
AstraZeneca
Small molecule
Ranibizumab
VEGF
Genentech
Monoclonal antibody
Pegaptanib
VEGF
OSI/Pfizer
Small molecule
Sorafenib
Multiple targets
Onyx/Bayer
Small molecule
Dasatinib
Multiple targets
BMS
Small molecule
Sunitinib
Multiple targets
Pfizer
Small molecule
Erlotinib
EGFR
Genentech/Roche
Small molecule
Nilotinib
Bcl-Abr
Novartis
Small molecule
Lapatinib
EGFR/Erb2
GSK
Small molecule
Panitumumab
EGFR
Amgen
Monoclonal antibody
+ many more