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Proliferation
Differentiation
Senescence
Apoptosis
Inflammation
Dörr et al., RTO ( 2005)
oral mucosa, mouse ulcer induction
10x3 Gy
0
2
4
6
8
10
12
14
16
Palifermin treatment protocol
ED50 of test irradiation [Gy]
n ≥ 5x10
Keratinocyte Growth Factor (Palifermin)
Intervention with signaling