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Ginger Medicinal Uses
Pharmacology (WHO)
Cholagogic activity
Intraduodenal administration of an acetone extract (mainly essential
oils) of ginger root to rats increased bile secretion for 3 hours after
dosing. The active constituents of the essential oil were identified as
[6]-
and
[10]-gingerol
.
Antiemetic activity
The antiemetic action of ginger has been attributed to the combined
action of
zingerones
and
shogaols
.
Anti-inflammatory activity
In vivo
studies have shown that oral administration of ginger extracts
decreased rat paw edema. The potency of the extracts was
comparable to that of acetylsalicylic acid.
[6]-Shogaol
inhibited
carrageenan-induced paw edema in rats by inhibiting cyclooxygenase
activity.