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Nodal Radiotherapy Sub-study
-Start April 2016
Aim:
To show that a 5-fraction schedule of adjuvant radiotherapy to levels 1-3
axilla and/or level 4 axilla is non-inferior to a 15-fraction standard in terms
of patient reported arm swelling and function and to contribute additional
information to the endpoints of the main trial
Primary endpoint: Ipsilat tumour control
(personal communication, M Brunt)
Sec endpoints: PROMs
Sample size: 627 patients randomised 1:1:1 to 3 arms
August 2017: 202 patients accrued