1102 / 1816
FRACTIONATION, severe hypofractionation cont.
HAI-5-III trial: partially randomised patient preference trial, comparing adjuvant
hypofractionated RT in 15 versus 5 fractions after breast conservation or
mastectomy for early or locally advanced breast cancer in women above 65
years
Boost provided as SIB
Pts can accept randomisation or choose treatment
Primary endpoint:
breast retraction 2-5 years, BCCT core
Start Febr 2017
Expected accrual 798 patients
PI: Liv Veldeman, Ghent
(If regional nodes RT: 27 Gy/5 fr)
R
Women >65 years
Operated for early
BC or LABC with
an indication for
RT
28.5 Gy / 5
fr, 10 days
40 Gy / 15
fr, 3 weeks