1107 / 1816
Target for RT after PST, ongoing trials
cN1 NAC ypN0
NSABP B-51
Standard versus comprehensive radiotherapy in treating patients with no
residual nodal disease after NAC
cT1-3N1M0
Needle biopsy demonstrating nodal disease before NAC
NAC
Surgery + ALND/SNB with nodal pCR
Randomisation
BCS: WBI vs WBI + RNI
Mastectomy: PMRT (chest wall + RNI) vs no PMRT
N=1636
Start 2013, estimated end of accrual 2023
Primary endpoint: any event (LR, RR, DM, death)