1129 / 1816
Improved survival by treatment escalation
Systemic treatment
• in terms of number of drugs
• dose (sometimes)
• duration of therapy
Increasing number of breast cancer survivors
Focus on quality of life, limiting morbidity
Trials addressing de-escalation of treatment to
reduce morbidity without significantly
compromising survival are of increasing importance.
It seems unlikely that further escalation of adjuvant chemotherapy will improve
survival, except in selected subgroups
19-9-2017