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Conundrum of PST: current evidence

Mamounas E. et al. JCO 2012;30:3960-6 - Buchholz TA, et al. JCO 2001;20:17-23 - Krug D, et al. JCO 2015;33:A 1008.

Indications for post-mastectomy RT

Factors that assist in decision making based on

retrospective analyses of NSABP-B18; NSABP-

B27; MDACC series; GBG Trial Meta-analysis:

Initial stage

Biological characteristics

Burden of residual disease

Response to chemotherapy