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TREATMENT PROTOCOL

Treatment arm A

Delayed-immediate reconstruction

Initial surgery

Skin sparing/nipple sparing

mastectomy and axillary surgery

silicone gel implant and mesh

PMRT

Final reconstruction 6 months later

Autologous

Flaps

Fat transfer

Implant-based

+/- ADM

Flap + implant

Fat transfer

Treatment arm B

Delayed reconstruction

Initial surgery

total mastectomy and axillary

surgery

PMRT

Final reconstruction 6 months later

Autologous

Flaps

Fat transfer

Implant-based

+/- ADM (?)

Flap + implant

Fat transfer

The DBCG RT Recon Trial