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Mean heart dose (Gy)

0

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Number of study subjects

0 2 4 6 8 10 12 14 16 18 20 22 24 26 28

Distribution of mean heart doses in case-control study of MCEs

after breast cancer RT

NEJM 2013; 368:987-98

Average of mean heart doses

MCE cases: 5.4 Gy

Controls: 4.5 Gy