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Mean heart dose (Gy)
0
100
200
300
400
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600
Number of study subjects
0 2 4 6 8 10 12 14 16 18 20 22 24 26 28
Distribution of mean heart doses in case-control study of MCEs
after breast cancer RT
NEJM 2013; 368:987-98
Average of mean heart doses
MCE cases: 5.4 Gy
Controls: 4.5 Gy