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EBCTCG: Effect of RT after BCS on recurrence and

breast cancer mortality in pN0 women

In the randomised trials, the

proportional benefit of RT

after BCS similar across

categories of age, tumour

grade and tumour size, etc.

Proportional effects of

individual treatments also

stable against different

background treatments and

across calendar year

NB certain exceptions:

hormonal therapy in ER+ vs

ER-, RT after Mast in pN0 vs

pN+

EBCTCG, Lancet, 2011; 378:1707