216 / 1816
N =361 patients (1991-1998); age 45–75 years
pT1pN0M0; GI-II; ER+
Median follow-up of 5.9 years
2x2 clinical trial of factorial design:
•
+/- radiotherapy &
•
+/- tamoxifen (2 years)
Winzer K-J, et al. Eur J Cancer. 2004;40:998–1005.
Less local treatment: The role of RT in BCT