Early stage, low risk
(DCIS; T1G1-2; T2G1)
:
LC >>> DM: SX/RT
Early stage, high risk
(T1G3; T2G2-3; N1a)
:
LC: SX/RT
effect
by
Syst.Th.
DM: Syst.Th.importance LC
: need for SX/RT
Late stage
(T3-4; N2a-3)
:
DM >>> LC:
Syst.Th.
importance of LC: SX/RT
Poortmans P. Lancet. 2014 Jun 21;383(9935):2104-6.
Less local treatment: interaction loc-syst T