ESTRO Multidisciplinary Management of Breast Cancer 2017

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Early stage, low risk (DCIS; T1G1-2; T2G1) :
 LC >>> DM: SX/RT
Early stage, high risk (T1G3; T2G2-3; N1a):
 LC: SX/RT effect  by
 DM: . importance LC  : need for SX/RT
Late stage (T3-4; N2a-3):
 DM >>> LC: .  importance of LC: SX/RT
Poortmans P. Lancet. 2014 Jun 21;383(9935):2104-6.
Less local treatment: interaction loc-syst T