1256-1257 / 2437
Primary CNS lymphoma
• Lymphoma with exclusive manifestation in the CNS
• Median age: ~ 60 years
• Incidence: approximately 0.5/100.000
=> increasing for unkown reasons
• Particular situation: HIV-associated CNS lymphomas
=> incidence decreasing since introduction of HAART
• Unclear pathogenesis => specific CNS tropism?