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Redefining subsets
Group A (WNT)
-15%
-Older children
-All had β catenin mutation (not found in other groups)
-Classic histology
-No metastasis
-Prognosis very good
Group B (SHH)
-25%
-Mostly desmoplastic
-Rarely metastatic
-Infants and adults
-Good prognosis for infants, intermediate for adults