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Page Background

Redefining subsets

Group A (WNT)

-15%

-Older children

-All had β catenin mutation (not found in other groups)

-Classic histology

-No metastasis

-Prognosis very good

Group B (SHH)

-25%

-Mostly desmoplastic

-Rarely metastatic

-Infants and adults

-Good prognosis for infants, intermediate for adults