1904-1905 / 2437
Chordoma and Chondrosarcoma
CHORDOMA
•
Presumed to arise from remnants of
primitive notochord
•
An embryonic precursor replaced by
mesodermal elements to form
vertebrae and skull base
•
0.84 per 1 000 000 (M>F)
•
Median age 58 (3 - 95)
•
Typically Midline
CHONDROSARCOMA
•
Arise from embryonal rests of
cartilaginous matrix that escape
reabsorption during endochondral
ossification
•
5 per 1 000 000 (M>F)
•
Median age 51 (1 – 102)
•
Appendicular > axial > soft tissue
•
Typically Off Midline
24/10/2017