Brain 17 Vienna

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PCV toxicities EORTC 26951 vs RTOG 9402

Toxicities (Grade 3/4)

EORTC

26951

RTOG

9402

Hematologic, any

46%

56%

Neutropenia

32%

42%

Thrombocytopenia

21%

37%

Anemia

7%

5%

Peripheral neuropathy

2%

8%

Nausea/vomiting

6%

8%

Toxicity leading to treatment stop

38%

20%