Brain 17 Vienna

960-961 / 2437

Efficacy outcomes – by molecular diagnosis/therapy
RT (A) ChT (B/C) RT (A) ChT (B/C) RT (A) ChT (B/C)
IDHwt IDHmut
(n=28) (n=30)
Non-Codel
(n=40)
Non-Codel
(n=43)
Codel
(n=35)
Codel
(n=31)
PFS
[years]
0.8 (0.4-
1.2)
0.8
(0.7-1.4)
3.0
(1.6-4.6)
2.1
(1.5-3.1)
8.7
(3.9-11.1)
7.5
(4.0-9.4)
TTF
[years]
1.5
(0.9-3.3
1.2
(0.8-3.2)
4
(2.6-6)
4.5
(2.6-5.3)
10.1
(6.5-nr)
8.1
(5.0-nr)
OS [years]
4.7
(1.9-5.9)
3.1
(1.1-5.7)
7
(4.8-9.2)
7.3
(4.7-8.6)
nr
(10-nr)
nr
(6.6-nr)
Wick et al., Neuro Oncol 2016