962-963 / 2437
Efficacy outcomes – across trial
RTOG 9402
2
EORTC 26951
1
NOA-04
RT PCV+RT RT RT+PCV RT
CT
PFS,
IDHwt/1p/19
q intact
1.0
1.2
0.6
0.8
0.8
0.8
OS,
IDHwt/1p/19
q intact
2.7
2.6
1.8
2.1
4.7
3.1
PFS, 1p/19q
codel
2.9
8.4
4.2 13.1
8.7
7.5
OS, 1p/19q
codel
7.3 14.7 9.3
Not
reached
Not
reached
Not
reached
1. van den Bent et al. J Clin Oncol 2013
2. Cairncross et al. J Clin Oncol 2013