192
EMR
EMT
AEMT
Paramedic
Extended
Adenosine (Adenocard)
Action
Onset
Antiarrhythmic
Half life < 10sec
Indications
Narrow Complex Tachycardia
Pediatric SVT
Adult Dose
6 mg rapid IVP
If ineffective, wait 2 minutes and administer 12 mg rapid IVP
If any change after the first 12 mg, repeat 12 mg rapid IVP as needed
Pediatric Dose
0.1 mg/kg rapid IVP (Max 6 mg)
0.2 mg/kg rapid IVP for second dose (Max 12 mg)
Contraindications
2
nd
and 3
rd
degree AVB, sick sinus syndrome, bradycardia or normal pulse rate, hypersensitivity to adenosine
Adverse Reactions
Cardiovascular: Facial flushing, headache, sweating, palpitations, chest pain, hypotension
Respiratory: Shortness of breath, chest pressure, hyperventilation
Central Nervous System: Lightheadedness, dizziness, tingling, numbness, apprehension, blurred vision, burning
sensation, heaviness in arms, neck, and back
Gastrointestinal: Nausea, metallic taste, tightness in throat, pressure in groin
Precautions
Adenosine will not convert atrial fib, atrial flutter, or VT to NSR. May be rarely associated with VF. The effects
of adenosine are antagonized by methylxanthines such as caffeine and theophylline. In their presence, larger
doses may be required or adenosine may not be effective. At the time of conversion to a sinus rhythm, a variety
of new rhythms may occur. Generally these last a short period and are normally corrected on their own with no
intervention.
Considerations
Adults: Flush with 20mL NS after each dose
Pediatrics: Flush with 5mL NS after each dose
IV at antecubital site is important.
Adenosine (Adenocard
®
)