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EMR
EMT
AEMT
Paramedic
Extended
Amiodarone (Cordarone)
Action
Onset
Antiarrhythmic
Potassium/Sodium/Calcium Channel Blocker
1-5 minutes
Peak effect 30 minutes
Indications
Pulseless VT/VF
Ventricular Tachycardia
Adult Dose
300mg Initial Cardiac Arrest Dose
150mg Second Cardiac Arrest Dose
Pediatric Dose
5mg/kg, not to exceed adult dose in Cardiac Arrest
Repeat at 5mg/kg up to 2 times. Max dose 15 mg/kg in Cardiac Arrest
Contraindications
Hypersensitivity to amiodarone or iodine, cardiogenic shock, heart blocks, sinus node dysfunction, bradycardia
Adverse Reactions
Cardiovascular: Bradycardia, hypotension, heart block, prolonged QT interval, congestive heart failure
Central Nervous System: Visual disturbances, photosensitivity, abnormal smell sensation, paresthesia, abnormal
gait, involuntary movement, hallucinations, parkinsonian symptoms, dizziness, malaise, tremors
Gastrointestinal: Nausea, vomiting
Integumentary: Rash
Oral: Dry mouth
Respiratory: Pulmonary inflammation, edema, shortness of breath, pleural effusion
Precautions
Use with caution in renal impaired patients, or patients taking medications to control blood pressure.
Amiodarone may interact with most opioid pain medications.
Considerations
Pregnancy category D.
Amiodarone (Cordarone
®
)