212 / 222
212
EMR
EMT
AEMT
Paramedic
Extended
Naloxone (Narcan)
Action
Onset
Narcotic antagonist
2 minutes
Indications
Unresponsiveness (Adult or Ped)
Overdose (Adult or Ped)
Adult Dose
4 mg IVP/IO (slowly) or IM, may repeat once in 5 minutes if no effect
2 mg via MAD (1 mL per nostril maximum)
Pediatric Dose
0.1 mg/kg IVP/IO/MAD, may repeat in 5 minutes if no effect. Maximum 2 mg.
Contraindications
Known hypersensitivity.
Adverse Reactions
Nausea, vomiting, sweating, tachycardia, increased blood pressure, tremulousness, seizures, and cardiac arrest
Precautions
Several instances of hypotension, hypertension, ventricular tachycardia and fibrillation, and pulmonary edema
have been reported. Most of whom had pre-existing cardiac disease. Have means to physically control the
patient prior to administering the narcan.
Considerations
Short half-life. All patients receiving narcan regardless of state of consciousness or alertness must be
transported to the hospital. They may revert to their original state when the effects of narcan diminish.
Naloxone (Narcan
®
)