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Radiomics

model HPV predictions vs molecular

assay p16

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M

all

p16

HPV-

HPV+

HPV predictions by M

all

vs. HPV by p16

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M

no art

p16

HPV-

HPV+

HPV predictions by M

no art

vs. HPV by p16

a

b

p<0.05

p<0.05

Consistent and significant split between survival curves for HPV+ and

HPV- determined by p16, M

all (including CT dental artefecats)

and M

no art

Leijenaar et al., Unpublished