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Confidence intervals

More patients increase reliability, decrease

uncertainty

Toxicity

No toxicity Proportion

New

technique

5

15

25% (9-49%)

Old

technique

10

15

40% (21-61%)

Toxicity

No toxicity Proportion

New

technique

20

60

25% (16-36%)

Old

technique

40

60

40% (30-50%)

p=0.05

p=0.45