Problem: publication bias
•
Consider two hypothetical studies:
•
Study 1: Pre-treatment CT based textural features do not
correlate with outcome in 120 HNSCC patients
•
Study 2: Pre-treatment CT based textural features is associated
with poor survival in 60 HNSCC patients
•
Which of those two have the highest chance of being accepted
in a high impact journal?
•
Which of these studies would have the highest chance of
staying in the drawer and never be submitted?




