858-859 / 1676
Radiation-induced toxicity
Comprehensive Individual Toxicity Risk profile (CITOR)
Side effects
TCF
W1 W2 W3 W4 W5 W6 W7
W12
M6 M12 M18 M24
Dysphagia (grade≥2)
5% 7% 15% 40% 55% 60% 60%
40%
25% 20% 18% 16%
Tube feeding dependent
0% 0% 2% 10% 23% 30% 32%
20%
10% 5% 3% 3%
Xerostomia (grade≥2)
2% 5% 15% 25%
40% 50% 55%
40%
30% 28% 26% 26%
Sicky saliva (grade≥2)
2% 7% 20% 28% 45% 53% 57%
36%
28% 20% 15% 10%
Loss of taste (grade≥2)
0% 4% 15% 40% 45% 50% 55%
50%
30% 15% 8% 7%
Oral mucositis (grade≥3)
0% 0% 5% 20% 40% 45% 48%
6%
Aspiration (grade≥3)
0% 0% 1% 4% 6% 7% 7%
8%
7% 6% 3% 3%
Osteoradionecrosis (grade≥3)
2%
4% 5% 5% 3%
Hypothyroidism (grade≥3)
5% 10% 18% 23%
Acute toxicity
Late toxicity
76
UMCG Radiation Oncology Head and Neck Prospective Data Registry