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Radiation-induced secondary cancer

after breast radiotherapy

Most second cancers after radiotherapy are attributed to other

factors, e.g. lifestyle and genetics

Berrington de Gonzales Lancet Oncol 2011

Contralateral breast cancer:

In patients < 40 years: if mean dose > 1 Gy (dose-dependent)

Stovall IJROBP 2008

Induction of non-breast cancer, e.g. lung, esophagus

Grantzau RO 2015