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Mr R, 80 years old

Prostate biopsy: Prostate cancer in right prostate lobe, Gleason score 6

Gleason score:

- based on patterns:

Pattern 1: normal prostate with small, well-formed glands

corresponds to a well differentiated carcinoma

Pattern 5: tissue does not have any or only a few prostate glands

corresponds to a poorly differentiated carcinoma

- grading: sum of dominant pattern and next-most frequent pattern

e.g. 3 + 4 = 7

Low-risk: Gleason score ≤ 6, High-risk: Gleason ≥ 8