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DRAFT AOAC SMPR 2015.XXX; Version 6; February 27, 2015
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Standard Method Performance Requirements for
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Quantitation of Arsenic Species in Selected Foods and Beverages
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Intended Use: Reference method for dispute resolution.
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Purpose
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AOAC
Standard Method Performance Requirements
SM
SMPR’s describe the minimum
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recommended performance characteristics to be used during the evaluation of a method. The
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evaluation may be an on-site verification, a single-laboratory validation, or a multi-site
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collaborative study. SMPRs are written and adopted by AOAC Stakeholder Panels composed of
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representatives from the industry, regulatory organizations, contract laboratories, test kit
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manufacturers, and academic institutions. AOAC SMPRs are used by AOAC Expert Review
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Panels in their evaluation of validation study data for method being considered for
Performance
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Tested Methods
or AOAC
Official Methods of Analysis
, and can be used as acceptance criteria for
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verification at user laboratories. [Refer to Appendix F:
Guidelines for Standard Method
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Performance Requirements
,
Official Methods of Analysis of AOAC INTERNATIONAL
(2012) 19th
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Ed., AOAC INTERNATIONAL, Gaithersburg, MD, USA.]
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Applicability
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Quantitation of arsenic (As) species and/or total inorganic arsenic in selected food and
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beverage matrixes (see table I for a list of selected foods.)
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Preferred Analytical Technique
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Separation of species by either ion chromatography (IC or high-performance liquid
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chromatography (HPLC and detection of separated species by inductively coupled plasma-mass
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spectrometry (ICP-MS).
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4 Definitions
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Arsenic Species
.— For the purposes of this SMPR arsenic species includes the compounds listed
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in table 2.
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Limit of quantitation (LOQ)
.—The minimum concentration or mass of analyte in a given matrix
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that can be reported as a quantitative result.
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Quantitative method.
—Method of analysis which response is the amount of the analyte
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measured either directly (enumeration in a mass or a volume), or indirectly (color, absorbance,
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impedance, etc.) in a certain amount of sample.
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Repeatability
.—Variation arising when all efforts are made to keep conditions constant by using
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the same instrument and operator and repeating during a short time period. Expressed as the
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repeatability standard deviation (SDr); or % repeatability relative standard deviation (%RSDr).
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