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2
Reproducibility
.—The standard deviation or relative standard deviation calculated from
49
among-laboratory data. Expressed as the reproducibility standard deviation (SDR); or %
50
reproducibility relative standard deviation (%RSDR).
51
52
Recovery
.—The fraction or percentage of spiked analyte that is recovered when the test
53
sample is analyzed using the entire method.
54
55
Total Inorganic Arsenic- The sum of arsenite and arsenate either reported as the sum of the
56
individual species or converted into one form and reported as the total.
57
58
59
5 Method Performance Requirement
s
60
61
See
table 3.
62
63
6
System suitability tests and/or analytical quality control
64
65
Suitable methods will include blank check samples, and check standards at the lowest point
66
and midrange point of the analytical range, and a protocol to demonstrate suitability.
67
68
7
Reference Material(s
69
70
Refer to Annex F:
Development and Use of In-House Reference Materials
in
Appendix F
:
71
Guidelines for Standard Method Performance Requirements
[19
th
Edition of the AOAC
72
INTERNATIONAL
Official
Methods
of
Analysis
(2012].
Available
at:
73
http://www.eoma.aoac.org/app_f.pdf74
75
8
Validation Guidance
76
77
Validation data must include at a minimum arsenite and arsenate, or total inorganic arsenic, in
78
the food types listed in table 1 that apply to the candidate method for First Action
Official
79
Methods of Analysis
approval. It is not required to represent every arsenic species or food type.
80
81
Appendix D
: Guidelines for Collaborative Study Procedures To Validate Characteristics of a
82
Method of Analysis;
19
th
Edition of the AOAC INTERNATIONAL Official Methods of Analysis
83
(2012. Available at:
http://www.eoma.aoac.org/app_d.pdf84
85
9 Maximum Time-To-Result
86
87
No maximum time to result.
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90
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92
93
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