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General Form of a

Dose Objective Function

 

 

1

1

i

H

i

j

N

j

p i

H

i

j

i

i

D d

D d

N

f

i

x

x

 

 

1

1

i

L

i

j

N

j

p

i

j

i

L

i

i

D d

d D

N

f

i

 

x

x

Low-Objective

D

L

= D

V

for V

100%

d

i

j

is the dose at the j

th

-sampling point for the i

th

-objective function:

 

cath

k

ASDP

N

k

N

l

i

jkl

lk

i

j

dx

d

1

1

2

~

(x)

Catheters/

Needles/

Applicators

Active SDPs

Dwell time t

lk

Inverse Optimisation and Planning: Objectives

High-Objective

D

H

= D

V

for V

0%