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• 248 patients 1996-2011

• BCS, EBRT + HDR 3x4.4Gy

• Whole breast RT (50 Gy)

• metallic needles

• HDR three fractions of 4.4Gy with optimization in volume

prescribed to the 85% isodose

• 3 x 4.7Gy to 90% isodose

• Two days at the hospital

• one night with the implant

Guinot JL, Tortajada MI, Santos MA et al. HDR boost decreases the risk of breast failure in

invasive breast carcinoma with close or involved margins. Presented at ESTRO 2017

HDR boost with close and positive margins

Guinot JL et al. Int J Radiat Oncol B P 2007; 68:1381-7