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EORTC 22881/10882 “boost”

Poortmans et al (actualized 2008) median FU 10.8y

Electrons

Photons Interstitial

Number

with boost

1635

(63%)

753

(28%)

225

(9%)

Total

2661

Median

boost dose

16 Gy

16 Gy

15 Gy

Median

boosted cc

144cc

288cc

60cc

10 y. Local

recurrence

6.3%

5.3%

3.7%

No boost

9.8%

Severe

fibrosis

3.8%

5.3%

5.3%

No boost

1.6%