CPB Budapest 2017

Polgár C, Fodor J, Major T, Breast-conserving treatment with partial or whole breast irradiation for low-risk invasive

breast carcinoma--5-year results of a randomized trial.Int J Radiat Oncol Biol Phys

. 2007

Nov 1;69(3):694-702.

National Institute of Oncology Budapest

(1998-2004)

•

258 pat. T1 N0-1

mic

G1-2, no lobular, EIC-, margins-,

•

FU 66m.

- 130 WBI 50 Gy

- 128 APBI

- 88 BT HDR 36.4 Gy (5.2 Gyx7)

- 40 electrons 50 Gy

•

Cosmesis good/excellent

63%

vs 77%

(p=0.009)

(

81%

HDR vs 70% e-

)

Update at 7 years .

•

Local failures:

3,3% vs 5,1%

(p=0,53)

•

Regional failure: 1,7% vs 1,6% (p= 0,99)

•

CSS

93,9% vs 96,2% (p=0,45)

•

89,4% vs 91,7% (p=0,44)

Budapest phase III APBI

Same

control,

better

cosmesis

2007