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Estudios FASE III en desarrollo

GEC-ESTRO Breast Brachy Working Group

WBI 50 Gy + e-10 Gy

(6 weeks)

interstitial multicatheter brachytherapy

(5 days)

HDR 8 x 4 Gy (32 Gy) or 7 x 4.3 Gy (30.1 Gy)

PDR: 50 Gy 0.60 – 0.80 Gy/hora (1 pulse/hour,

24 hours/day)

NSABP B-39/RTOG 0413 trial

WBI 50 Gy + 10-16 Gy (6-7weeks)

BT interstitial multicatheter 3,4 Gy x 10 frac (5 days)

BT intracavitary balloon

3,4 Gy x 10 frac (5 days)

3D EBRT

3,85 Gy x 10 frac (2 weeks)

Which is the optimal technique?

Is APBI equivalent to Whole Breast Irradiation?

Not yet

What do we need to know?