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Extranodal Lymphomas of Mucosa-
associated Lymphoid Tissue
•
Mainly indolent, composed of small cells
•
Believed to be driven by host immune reactions to chronic
infections or auto-immunity
•
Form distinctive lympho-epithelial lesions
•
Often prominent accompanying reactive lymphoid
components
•
Enteropathy-associated T-cell lymphoma is classified
separately
•
Tends to be aggressive, in part due to cytotoxic (perforin
etc.) phenotype