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Extranodal Lymphomas of Mucosa-

associated Lymphoid Tissue

Mainly indolent, composed of small cells

Believed to be driven by host immune reactions to chronic

infections or auto-immunity

Form distinctive lympho-epithelial lesions

Often prominent accompanying reactive lymphoid

components

Enteropathy-associated T-cell lymphoma is classified

separately

Tends to be aggressive, in part due to cytotoxic (perforin

etc.) phenotype