•
Localized aggressive disease: Systemic therapy is the primary treatment.
RT is used as consolidary treatment, dose 30-36 Gy after CR, 40-45 Gy if
gross residual disease
•
Radiation volumes may be limited to part of an organ after excellent
response to systemic treatment, which controls microscopic disease
•
Advanced aggressive disease: RT to initial bulk according to RICOVER
and UNFOLDER studies, extranodal disease unclear (Waldeyer’s ring was
not considered extranodal in RICOVER)
Head & neck lymphomas, aggressive