1131 / 1498
NK/T-cell lymphoma, nasal type
Courtesy of Dr. Shunan Qi, Memorial Sloan Kettering Cancer Center, New York, and Chinese Academy of Medical Sciences, Beijing
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Challenges for GTV contouring
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Lesions often associated with mucosa surface
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Lesions are accompanied with inflammation/necrosis
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Lesions sit in an area with rich lymphoid tissues
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Rationales guiding CTV contouring
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Experience with chemotherapy is limited (SMILE, non-MDR drugs)
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RT is the most effective treatment
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Close association between local control and survival
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Uncertainty of disease boundaries
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Local invasiveness of the disease nature
Extended ISRT!
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Irradiate the whole involved cavity and adjacent structures!