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Single agent rituximab in previously untreated patients

overall response rates: 50-87%

median time to disease progression <1 year

Treatment

Immunotherapy

Conconi et al. 2003; Ferreri et al. 2005; Benetatos et al. 2006; Heinz et al. 2007

90Y ibritumomab tiuxetan for front line treatment of stage IE

indolent OAL in 12 patients:

complete response in 10 patients

partial response in 2 patients

Esmaeili et al. 2009; Shome and Esmaeili 2008