1170 / 1498
•
A prospective phase II clinical trial
•
27 patients
(15 newly diagnosed and 12 relapsed)
•
Cp infection in 11 pts
•
Treatment:
doxycycline 100 mg orally twice daily for 3 weeks
•
CR/PR in 7 of 11 Cp-positive and 6 of 16 Cp-negative patients
•
ORR 48%
•
2-year FFS 66%
Treatment
Cp-eradicating antibiotic therapy
Ferreri et al, Ann Oncol, 2006