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Abrey, L. E. et al. J Clin Oncol; 18:3144-3150 2000

Overall survival of patients

> 60 years

who did (n = 12) or did not (n = 22)

receive whole-brain RT

without WBRT

with WBRT

Neurotoxicity-75%

Relapse-25%

Neurotoxicity-12%

Relapse-58%