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RT in PCNSL: Dose
•
Consolidation dose
after MRI-CR to chemotherapy:
23.4 Gy
in
1.8 Dose per fraction. (13 treatments)
•
WBRT
after incomplete
response to chemotherapy:
36 Gy to 45
Gy
(1.5 to 1.8 Gy/fraction)
•
WBRT for salvage of chemotherapy failure (progression or
relapse) 36 – 40 Gy
(1.5 Gy-1.8 Gy/fraction)
•
WBRT as
primary treatment
for non-candidates for
chemotherapy:
40-50 Gy
•
Whole orbit (if included)- only up to 36 Gy
•
For
palliation
: WBRT dose is
30-36 Gy
in 10 or 15 fractions.